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Independent Enzyme
Production for
Lignocellulosic
Biochemicals

Unlock independent biochemical production from lignocellulosic biomass through on-site enzyme production, designed for adaptable processing and scalable operations

With rising demand for sustainable biochemicals, lignocellulosic biomass is emerging as a key feedstock. Its robust structure calls for more adaptable processing, fueling interest in flexible and independent enzyme production approaches.

A New Approach with
On-Site Production

On-site enzyme production enables enzymes to be produced within a bioethanol facility. By bringing production closer to operations, facilities can better align supply with real-time needs and improve overall process efficiency. The system integrates into existing processes, supporting a scalable and reliable enzyme supply.

Onsite enzyme production scheme for direct use at a biorefinery plant

Why On-site Enzyme Production?

Biochemical facility with corn biomass for onsite enzyme cost reduction

Reducing Costs in Enzyme Supply

In bioethanol production from lignocellulosic biomass, enzymes are required in large volumes to support saccharification. Supplying these enzymes externally involves transport, storage, and handling, which can add cost. Producing enzymes on-site for biomass processing helps reduce these steps, paving the way for cost reduction as operations scale.

Onsite enzyme testing for lower-carbon biomass residue processing

Lower Carbon Emissions Through Independent Production

Enzyme supply for bioethanol production often involves multiple transport and handling steps, contributing to emissions. By producing enzymes on-site, facilities reduce transport requirements and move toward an independent production model, supporting lower carbon output and operational flexibility.

How Does It Work?

Kao supports bioethanol production through a flexible on-site enzyme manufacturing model tailored to plant design, biomass type, and available engineering resources.

Turnkey Delivery for Complete Operational Readiness

Turnkey delivery onsite enzyme production workflow from design to operation

A complete on-site enzyme production system is delivered through leased microbial strains and a Kao engineering partner, providing end-to-end delivery from design to construction. The customer's role is to commission the project, then take over a completed facility with enzyme engineering capabilities. By managing the full process, this turnkey solution reduces complexity, lowers execution risk, and is well suited for facilities looking to fully outsource implementation and receive a ready-to-operate plant.

Built Around Your Operations

Different implementation approaches can be considered depending on facility requirements and internal capabilities. We help identify a setup aligned with each operation.

How Will This Scheme Work for You?

Example 1

A large-scale bioethanol facility in India processing rice straw and wheat straw, operating continuously with high enzyme demand

Solution

For facilities with strong engineering capabilities, on-site enzyme production can be handled in-house. Kao leases microbial strains, making it easier to integrate production into existing systems while maintaining control over design, scale, and cost. This helps align enzyme supply with process needs while reducing industrial emissions linked to transport and external sourcing.

Example 2

A biorefinery in Thailand producing bioethanol and bio-based products from sugarcane bagasse, rice straw, and cassava biomass with biochemical enzymes

Solution

Implementing on-site enzyme production requires expertise in process design and equipment integration. A hybrid approach helps simplify this by combining Kao’s microbial strains with engineering support from partners, allowing key parts of the system to be handled externally while the facility retains control over construction and operations.

Example 3

A bio-based chemicals producer in France processing cereal residues and forestry biomass using industrial enzymes, looking to reduce emissions

Solution

Sustainability-focused operations often assess emissions across the full production chain, including transport. Supplying enzymes from external locations adds to overall carbon output. A turnkey approach enables fully integrated on-site enzyme production—from design to construction—helping reduce transport-related emissions while supporting a more transparent and optimized production system.

Example 4

A sugar and bioethanol producer in Brazil processing bagasse, expanding into on-site enzyme production without internal engineering resources

Solution

Relying on external enzyme delivery can create operational risk across the supply chain. A turnkey approach enables end-to-end implementation of on-site enzyme production—from design to construction—managed by engineering partners. This reduces dependence on external logistics while ensuring reliable operations with minimal internal involvement.

Looking for the Right Setup?

Off-Site Enzymes for Biomass Conversion

For facilities processing lignocellulosic biomass, Kao offers ready-made enzyme solutions. CRESCENTISTM supports saccharification in bioethanol production and is available through conventional supply, with the option to transition on-site.

Our Global Presence

Kao operates globally across Asia, the Americas, and Europe, guided by sustainability and innovation. Its chemical business supports materials, energy, and bio-based production, contributing to advanced industrial and bio-based applications.

About
Kao Global Chemicals Japan

Kao is a Japan-based company with a long history in chemicals and research development. Drawing on expertise across consumer and industrial fields, it develops enzyme and bio-based solutions that support sustainability and bio-based production.

Kao head office in Japan

Kao chemical research facility

Industry Recognition

Awards and recognitions from global organizations reflecting our commitment to responsible and sustainable business practices.

  • Kao's CDP 2024 Triple A rating for climate, forests, and water security

  • Kao's Ethisphere World's Most Ethical Companies award recognition

  • Kao's CDP Supplier Engagement Leader 2024 award recognition

  • Kao's Prime Corporate ESG Performance award recognition

  • Kao's European Responsible Care Awards recognition

News & Annoucements

Ready to Improve Saccharification Performance for Your Specific Feedstock?

Kao offers on-site enzyme models for biomass processing and bioethanol production.
Get in touch to explore the most suitable approach for your operations.

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