Global Chemicals Japan

Bio Gallic Acid GA-100 BIO

Creating from and for nature

Kao has developed a fermentative production technology that uses microorganisms to produce gallic acid from glucose. Gallic acid is a basic raw material used in a wide variety of business fields, including electronics, industry and food.

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Kao Gallic Acid GA-100 BIO

Gallic acid is widely used as a semiconductor-related material in electronic devices such as personal computers and smart phones, and as anti-rust for boilers. Despite its industrial importance, it is found in gallnuts and tara, the production area is limited, and yields are easily affected by weather conditions.

Kao focused on the fermentation technology using glucose and continued to develop a practical production technology and succeeded in introducing multiple gallic acid production pathways into Coryneform bacteria and inhibiting the metabolic pathway of by-product residence.

With this technology, we have established a new supply chain that enables highly efficient production and stable supply of gallic acid.

Features of Gallic Acid GA-100 BIO


  1. Features
    1. 1Stable supply unaffected by seasonal fluctuations
    2. 2Environmentally friendly manufacturing method
    3. 3No limitation of country of origin

Image of fermentative production of Gallic Acid

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Main physical properties

Properties White to light brown yellow crystals or crystalline powder
Purity > 99%
Loss on drying < 10.5%
Ignition residue < 0.10%
Heavy metal as Pb < 20ppm

Application examples

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Case studies

Application to water treatment chemicals for boilers

Kao has confirmed that GA-100 BIO, Kao's gallic acid, exhibits performance comparable to that of current products in a comparative study of the anti-corrosion effect on steel chips using a small once-through boiler. Kao has received the notification from the United States Food and Drug Administration (FDA) that "Gallic Acid and its salts are used in water boilers, at a level of 100 ppm, at temperatures exceeding 160℃ to prevent corrosion. The steam generated from the water boiler is then used to heat the food processing reactor's outer jacket. Based on analyses, the Gallic Acid and its salts are not present in the steam down to the part per million level. Furthermore, the steam is used in the food processing reactor's outer heating jacket (closed system) . Therefore, the steam with any possible residual gallic acid will not be in direct or indirect contact with food or food contact surfaces". This encourages to promote not only domestic development but also overseas expansion.

Advantages of implementation

Environmental Considerations

Stability of production

Diversification of Supply Chain

Flow of implementation

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